大鼠脑和牛肾上腺嗜铬颗粒中一种高分子量形式的甲硫氨酸脑啡肽-精氨酸6-甘氨酸7-亮氨酸8 。
A high molecular weight form of met5-enkephalin-arg6-gly7-leu8 in rat brain and bovine adrenal chromaffin granules.
作者信息
Lindberg I, Yang H Y, Costa E
出版信息
Life Sci. 1983;33 Suppl 1:5-8. doi: 10.1016/0024-3205(83)90430-7.
An antiserum against met5-enkephalin-arg6-gly7-leu8 (MAGL) has been used to identify various molecular weight forms of this immunoreactive material in brain and adrenal tissue. The predominant immunoreactive species in acid extracts of chromaffin granules eluted on Biogel P-30 as an approximately equal to 8,000 dalton peptide. Acid extracts prepared from rat brain medulla-pons also contained 8,000 dalton immunoreactive material which exhibited an identical retention time on HPLC to the corresponding immunoreactive material prepared from chromaffin granules.
一种针对甲硫氨酸脑啡肽-精氨酸-甘氨酸-亮氨酸（MAGL）的抗血清已被用于鉴定脑和肾上腺组织中这种免疫反应性物质的各种分子量形式。嗜铬粒蛋白颗粒酸提取物中的主要免疫反应性物质在Biogel P - 30上洗脱时为一种分子量约为8000道尔顿的肽。从大鼠脑髓质-脑桥制备的酸提取物中也含有8000道尔顿的免疫反应性物质，其在高效液相色谱（HPLC）上的保留时间与从嗜铬粒蛋白颗粒制备的相应免疫反应性物质相同。
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