• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

孕期酒精对大鼠新生儿反射发育的影响。

Effects of gestational alcohol on the development of neonatal reflexes in the rat.

作者信息

Cogan D C, Cohen L E, Sparkman G

出版信息

Neurobehav Toxicol Teratol. 1983 Sep-Oct;5(5):517-22.

PMID:6664409
Abstract

The offspring of rats fed a diet containing 10% (v/v) of ethanol were tested for developmental differences from controls on a variety of maturational events and reflexes. Results indicated slower development of fur onset and ear (pinnae) opening, more rapid and vigorous righting responses and shorter dowel-grasping times in the offspring of ethanol-fed dams. No differences in rooting reflex, Babinski reflex, or in the visual placing response were found. These findings were seen as consistent with the interpretation that gestational alcohol exposure results in reduction in the ability of subjects to inhibit responses. The reduction in inhibition is not inconsistent with damage to the hippocampal area of the brain.

摘要

给喂食含10%(体积/体积)乙醇饮食的大鼠后代,就各种成熟事件和反射与对照组进行发育差异测试。结果表明,喂食乙醇的母鼠后代的毛发生长起始和耳朵(耳廓)张开发育较慢,翻正反应更快且更有力,抓棒时间更短。未发现觅食反射、巴宾斯基反射或视觉放置反应有差异。这些发现被认为与以下解释一致:孕期酒精暴露会导致受试者抑制反应的能力下降。抑制能力的下降与大脑海马区受损并不矛盾。

相似文献

1
Effects of gestational alcohol on the development of neonatal reflexes in the rat.孕期酒精对大鼠新生儿反射发育的影响。
Neurobehav Toxicol Teratol. 1983 Sep-Oct;5(5):517-22.
2
Development and learning in the offspring of rats fed an alcohol diet on a short- or long-term basis.短期或长期喂食酒精饲料的大鼠后代的发育与学习
Neurobehav Toxicol Teratol. 1985 Mar-Apr;7(2):129-37.
3
Developmental and behavioral effects of maternal alcohol exposure in rats.
Yakubutsu Seishin Kodo. 1982 Jul;2(1):39-46.
4
Does prenatal stress affect the motoric development of rat pups?产前应激会影响幼鼠的运动发育吗?
Brain Res Dev Brain Res. 2004 Apr 19;149(2):85-92. doi: 10.1016/j.devbrainres.2003.12.008.
5
Effect of fetal ethanol exposure on the in vitro release of growth hormone, somatostatin and growth hormone-releasing factor induced by clonidine and growth hormone feedback in male and female rats.胎儿乙醇暴露对雄鼠和雌鼠体内可乐定诱导的生长激素、生长抑素及生长激素释放因子的体外释放以及生长激素反馈的影响。
Alcohol Clin Exp Res. 1997 Aug;21(5):826-39.
6
Prenatal ethanol exposure diminishes activity-dependent potentiation of amino acid neurotransmitter release in adult rat offspring.产前乙醇暴露会削弱成年大鼠后代中氨基酸神经递质释放的活动依赖性增强。
Alcohol Clin Exp Res. 1998 Nov;22(8):1771-7.
7
Prenatal ethanol exposure increases ethanol reinforcement in neonatal rats.产前乙醇暴露会增加新生大鼠对乙醇的强化作用。
Alcohol Clin Exp Res. 2006 Jan;30(1):34-45. doi: 10.1111/j.1530-0277.2006.00009.x.
8
NTP technical report on the toxicity studies of Dibutyl Phthalate (CAS No. 84-74-2) Administered in Feed to F344/N Rats and B6C3F1 Mice.美国国家毒理学计划关于邻苯二甲酸二丁酯(化学物质登记号84 - 74 - 2)经饲料给予F344/N大鼠和B6C3F1小鼠的毒性研究技术报告。
Toxic Rep Ser. 1995 Apr;30:1-G5.
9
Effects of prenatal and postnatal maternal ethanol on offspring response to alcohol and psychostimulants in long evans rats.产前和产后母体乙醇对长 Evans 大鼠后代对酒精和精神兴奋剂反应的影响。
Neuroscience. 2009 Jun 30;161(2):427-40. doi: 10.1016/j.neuroscience.2009.03.076. Epub 2009 Apr 5.
10
Alcohol exposure before pregnancy: effect on GABA levels and turnover in rat offspring.孕期前酒精暴露:对大鼠后代γ-氨基丁酸水平及代谢的影响
Alcohol Alcohol. 1993 Mar;28(2):175-9.

引用本文的文献

1
Teratogenic and behavioral anomalies induced by acute exposure of mice to ethanol and their possible relation to fetal brain DNA synthesis.小鼠急性暴露于乙醇所致的致畸和行为异常及其与胎儿脑DNA合成的可能关系。
Pharm Res. 1988 Jul;5(7):447-52. doi: 10.1023/a:1015996603418.