Isseroff A, Madar Y
Neurosci Lett. 1983 Nov 11;41(3):277-82. doi: 10.1016/0304-3940(83)90463-9.
We present data from autoradiography of 2-deoxyglucose (2-DG), which indicate that despite the limited uncrossed optic innervation of the rat, monocular stimulation produces considerable activation of ipsilateral primary visual centers. Compared to binocularly occluded rats, intact, monocularly occluded ones showed substantial and statistically significant increases in 2-DG uptake throughout the dorsal lateral geniculate nucleus and superficial layers of the superior colliculus ipsilateral to the stimulated eye, as well as larger increases in contralateral areas. In contrast, stimulation of mono-enucleated rats did not produce observable increases in 2-DG uptake in ipsilateral optic centers, confirming previous results. This effect may be due to functional depression in the denervated areas.
我们展示了2-脱氧葡萄糖（2-DG）放射自显影的数据，这些数据表明，尽管大鼠的视交叉未交叉神经支配有限，但单眼刺激会使同侧初级视觉中枢产生相当程度的激活。与双眼闭塞的大鼠相比，完整的、单眼闭塞的大鼠在受刺激眼同侧的整个背外侧膝状核和上丘浅层中，2-DG摄取量显著且有统计学意义地增加，对侧区域的增加幅度更大。相比之下，对单眼摘除大鼠的刺激并未使同侧视觉中枢的2-DG摄取量出现可观察到的增加，这证实了先前的结果。这种效应可能是由于去神经支配区域的功能抑制。
