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[白塞病的止血参数]

[Parameters of hemostasis in Behçet's disease].

作者信息

Dupuy E, Tobelem G, Bourgeois P, Soria C, Pellerin A, Bellucci S, Caen J P

出版信息

Rev Med Interne. 1983 Dec;4(4):317-21. doi: 10.1016/s0248-8663(83)80053-8.

Abstract

Venous thrombosis occurred frequently in Behçet's disease. In 12 patients with Behçet's disease of whom 6 have had leg venous thrombosis, some parameters of hemostasis or fibrinolysis have been studied. Platelet count, fibrinogen level, factor VIII coagulant activity, factor VIII antigen, plasminogen and antithrombin III level were in the normal range. Fibrinolytic capacity in response to venous occlusion of the arms was the same in patients and in healthy subjects, in the patients, there was no difference in regard to the occurrence of venous thrombosis. These parameters seemed therefore not able to detect the thrombotic tendency in this disease. These results are discussed with the other reports of the literature.

摘要

静脉血栓形成在白塞病中频繁发生。在12例白塞病患者中,其中6例有下肢静脉血栓形成,对一些止血或纤溶参数进行了研究。血小板计数、纤维蛋白原水平、凝血因子Ⅷ促凝活性、凝血因子Ⅷ抗原、纤溶酶原和抗凝血酶Ⅲ水平均在正常范围内。患者和健康受试者对上肢静脉闭塞的纤溶能力相同,在患者中,静脉血栓形成的发生率没有差异。因此,这些参数似乎无法检测出该疾病的血栓形成倾向。本文结果与文献中的其他报道进行了讨论。

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