Bhagyalakshmi A, Sreenivasula Reddy P, Ramamurthi R
Toxicol Lett. 1983 Sep;18(3):277-84. doi: 10.1016/0378-4274(83)90107-8.
Adult crabs were exposed to 3 concentrations of sumithion with a control group over a 20-day period. Hemolymph glucose levels were monitored in each group over the course of the experiment. The group demonstrating the most acute and sustained hyperglycemia (2 ppm sumithion) was then analyzed, as also the controls for changes in hepatopancreas glycogen, total carbohydrates, phosphorylase and aminotransferases. Significant (P less than 0.001) depressions in hepatopancreas glycogen and total carbohydrates and elevations of phosphorylase and transaminases were observed in sumithion-stressed crabs when compared with controls. These changes are discussed with respect to gluconeogenesis and possible influences of hyperglycemic hormone, which is released into hemolymph of stressed crab.
成年螃蟹在20天的时间里暴露于3种浓度的杀螟硫磷中,并设置了一个对照组。在实验过程中监测了每组螃蟹的血淋巴葡萄糖水平。然后对表现出最急性和持续性高血糖的组(2 ppm杀螟硫磷)进行了分析,同时也分析了对照组肝胰腺糖原、总碳水化合物、磷酸化酶和转氨酶的变化。与对照组相比,在杀螟硫磷胁迫的螃蟹中观察到肝胰腺糖原和总碳水化合物显著降低(P小于0.001),磷酸化酶和转氨酶升高。针对糖异生以及释放到受胁迫螃蟹血淋巴中的高血糖激素的可能影响,对这些变化进行了讨论。