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[脾脏异位自体移植的初步临床经验]

[Primary clinical experience with heterotopic autologous transplantation of the spleen].

作者信息

Jekić M

出版信息

Acta Chir Iugosl. 1983;30(2):211-9.

PMID:6666472
Abstract

On the basis of research and results obtained in recent years that the removing of the spleen increases an aptitude to the infection, the authors have carried out in 1981-1982 four autotransplantations of the spleen; they did it in polytraumatised patients with an extensive rupture of the spleen, where, because of the safe haemostasis, only a splenectomy should have to be performed. By a new technique, removed ruptured spleen is prepared with special procedure, and it is transplanted into the omentum majus of the same patient. There were no complications, although it is concerned of a few patients and a short postoperative follow-up. Three to four months after surgery, the Howwel-Jolly bodies became normal as well as vacuolated erythrocytes and immunophoresis, so that it corresponds to the normal, in-situ, spleen activity; it means that it is to expect a sufficient protection against an infection.

摘要

基于近年来所获得的研究及结果,即脾脏切除会增加感染易感性,作者于1981年至1982年进行了4例脾脏自体移植手术;手术对象为脾脏广泛破裂的多发伤患者,由于止血安全,原本只需进行脾切除术。采用一种新技术,将切除的破裂脾脏通过特殊程序处理后,移植到同一患者的大网膜中。尽管涉及患者数量较少且术后随访时间较短,但未出现并发症。术后三到四个月,豪威尔-乔利小体、空泡化红细胞及免疫电泳均恢复正常,这与正常原位脾脏的活性相符;这意味着有望获得足够的抗感染保护。

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