Wesseling H, Houwertjes M C, de Langen C D, Kingma J H
Arch Int Pharmacodyn Ther. 1983 Nov;266(1):106-12.
4-Aminopyridine (1 mg/kg) restored a 35% fall in arterial blood pressure in rabbits evoked by a verapamil infusion (0.5 mg/kg/min) more effectively than calcium-levulate (approx. 13 mg/kg). However, the lethal dose of verapamil for rabbits (mean: 7.1 mg/kg given by intravenous infusion in 14.3 min) was not affected by 4-aminopyridine pretreatment.
