Abstract
Two tumors of B lymphocytes, murine plasmacytomas and human Burkitt's lymphoma, display characteristic chromosomal translocations. Molecular cloning studies have shown that these tumors have translocated an oncogene, called C'MYC, into the antibody gene locus. This oncogene translocation probably contributes to but is not sufficient for the occurrence of these tumors.
摘要
两种B淋巴细胞肿瘤，即鼠浆细胞瘤和人类伯基特淋巴瘤，表现出特征性的染色体易位。分子克隆研究表明，这些肿瘤已将一种名为C'MYC的癌基因易位到抗体基因位点。这种癌基因易位可能促成但不足以导致这些肿瘤的发生。
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