Cazzato G, Zorzon M, Monti F
Riv Neurol. 1983 Nov-Dec;53(6):369-78.
The time of onset of the neurological symptomatology was studied retrospectively in 258 patients, 107 (41%) autopsized, affected by non embolic cerebral infarction (172 cases), cerebral haemorrhage (52 cases) and subarachnoid haemorrhage (24 cases). In the patients suffering from cerebral infarction or haemorrhage the symptomatology began more frequently in the morning hours (from 6 to 12 a.m.) while it was comparatively rare in the night (from 00 to 06 am.). and evening hours (from 6 to 12 p.m.). This difference was significant (p less than 0.01) at the chi-squared test. The patients with subarachnoid haemorrhage showed a more homogeneous distribution with a higher but not significant frequency in the morning hours. The nyctohemeral distribution does not significantly differ in the patients affected by cerebral infarction, cerebral haemorrhage and subarachnoid haemorrhage. The time of onset of the neurological symptomatology shows no significant variation in the patients with cerebral and subarachnoid haemorrhage after dividing them in normotensives and hypertensives, while in the hypertensive patients with cerebral infarction a significant higher frequency of strokes was observed in the night hours (from 00 to 06 a.m.).
对258例患者的神经症状出现时间进行了回顾性研究,其中107例(41%)进行了尸检,这些患者患有非栓塞性脑梗死(172例)、脑出血(52例)和蛛网膜下腔出血(24例)。在患有脑梗死或脑出血的患者中,症状更常于上午(上午6点至12点)开始出现,而在夜间(凌晨0点至6点)和傍晚(下午6点至12点)相对较少。在卡方检验中,这种差异具有显著性(p小于0.01)。蛛网膜下腔出血患者的分布更为均匀,上午出现症状的频率较高但无显著性差异。脑梗死、脑出血和蛛网膜下腔出血患者的昼夜分布无显著差异。将患有脑出血和蛛网膜下腔出血的患者分为血压正常者和高血压者后,神经症状出现时间无显著变化,而在患有脑梗死的高血压患者中,夜间(凌晨0点至6点)中风的频率显著更高。