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维持性血液透析患者的继发性甲状旁腺功能亢进:N端和C端甲状旁腺激素的研究

Secondary hyperparathyroidism in patients on maintenance hemodialysis: study of the N and C-terminal parathyroid hormones.

作者信息

Hida M, Shimbo T, Nakamura K, Wakabayashi T, Saitoh H, Satoh T

出版信息

Tokai J Exp Clin Med. 1983 Jul;8(3):225-8.

PMID:6670108
Abstract

In 34 dialysis patients without secondary hyperparathyroidism and 10 dialysis patients with secondary hyperparathyroidism, the concentration of parathyroid hormone, total calcium, ionized calcium, inorganic phosphate, total alkaline phosphatase and bone alkaline phosphatase in serum were determined. The following results were obtained: serum N and C-terminal parathyroid hormone levels, serum total and ionized calcium levels, and serum total and bone alkaline phosphatase levels in dialysis patients with secondary hyperparathyroidism were higher than the corresponding values in cases of negative secondary hyperparathyroidism. Serum phosphate levels in dialysis patients with and without secondary hyperparathyroidism did not differ. Serum bone alkaline phosphatase activities were well correlated with serum total alkaline phosphatase activities in patients on hemodialysis.

摘要

在34例无继发性甲状旁腺功能亢进的透析患者和10例继发性甲状旁腺功能亢进的透析患者中,测定了血清中甲状旁腺激素、总钙、离子钙、无机磷、总碱性磷酸酶和骨碱性磷酸酶的浓度。结果如下:继发性甲状旁腺功能亢进的透析患者血清N端和C端甲状旁腺激素水平、血清总钙和离子钙水平以及血清总碱性磷酸酶和骨碱性磷酸酶水平高于继发性甲状旁腺功能亢进阴性患者的相应值。有和无继发性甲状旁腺功能亢进的透析患者血清磷水平无差异。血液透析患者的血清骨碱性磷酸酶活性与血清总碱性磷酸酶活性密切相关。

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