Venosa R A
Biochim Biophys Acta. 1978 Jul 4;510(2):378-83. doi: 10.1016/0005-2736(78)90038-x.
The fractional loss of 22 Na+ from frog sartorius muscle is increased when the tonicity of the external solution is reduced. The effect, which is larger the lower the osmolarity, exhibits the following characteristics: (1) quick onset and reversibility, (2) is not reduced in the absence of external Na+, (3) is completely abolished by strophanthidin (3. 10-5 M), (4) is neither the result of membrane depolarization nor K+ accumulation in the extracellular space.
当降低外部溶液的张力时,青蛙缝匠肌中22Na+的分数损失会增加。这种效应在渗透压越低时越大,具有以下特征:(1)起效快且可逆;(2)在无外部Na+时不降低;(3)被毒毛花苷(3×10-5M)完全消除;(4)既不是膜去极化的结果,也不是细胞外空间中K+积累的结果。