Frolov A F, Barshteĭn Iu A, Anisimova Iu N
Arkh Patol. 1983;45(12):44-51.
Examinations of the section material of fatal cases due to leptospirosis and influenza, as well as examinations of organs in experimental toxic influenza by light and electron microscopy with determinations of the infectious and immune complexes showed leptospira and influenza virus to be capable of causing toxico-infectious shock (TIS) with typical changes in the microcirculatory bed and organ parenchyma. TIS should be considered to be a special form of the course of an infectious process in which different organs may be "shock organs" depending on the tropic properties of the causative agent: in leptospirosis - the kidneys and liver, in influenza - the lungs and brain.
对钩端螺旋体病和流感致死病例的切片材料进行检查,以及通过光学和电子显微镜对实验性中毒性流感的器官进行检查,并测定感染性和免疫复合物,结果表明钩端螺旋体和流感病毒能够引起中毒性感染性休克(TIS),伴有微循环床和器官实质的典型变化。应将TIS视为感染过程的一种特殊形式,其中根据病原体的嗜性特性,不同器官可能成为“休克器官”:在钩端螺旋体病中为肾脏和肝脏,在流感中为肺和脑。