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[通过计算机断层扫描评估脑死亡]

[Evaluation of brain death by computed tomography].

作者信息

Shiogai T, Takeuchi K

出版信息

No To Shinkei. 1983 Dec;35(12):1229-39.

PMID:6671075
Abstract

The absence of cerebral circulation and electrocerebral silence have served as an accurate index of irreversible brain death. It is proposed that computed tomography (CT) findings be evaluated as confirmatory criteria of brain death. To this end, CT evaluation of 14 patients satisfying the conventional criteria of brain death was performed. A.CT finding of severe compression or disappearance of the ventricular system, or so-called "brain tamponade", was seen in 7 (50%) of the 14 patients. Enhanced contrast CT, especially dynamic CT, usually distinctly reveals the cerebral vessels whenever the cerebral blood flow is preserved; conversely, the lack of enhanced brain structures, even comparing attenuation values, indicates the absence of cerebral blood flow. In 7 (70%) of 10 patients, however, there was enhanced contrast of vascular brain structures, especially the circle of Willis, major cerebral arteries, choroid plexuses, and venous sinuses. It is suggested that this result is due to the improvement of demonstrability by CT. The usefulness of CT in the confirmation of brain death lies in visualization of the pathological changes associated with a dead brain, such as "brain tamponade", and the lack of enhanced contrast indicating the absence of cerebral blood flow. The latter point is still problematic as angiography revealed an extremely low cerebral blood flow in a few cases of "dead brain" patients. It is recommended that cerebral blood flow in brain death be evaluated by dynamic CT scanning and correlated with other methods of cerebral blood flow determination (e.g., intravenous digital subtraction angiography).

摘要

脑循环缺失和脑电静息一直被视为不可逆脑死亡的准确指标。有人提议将计算机断层扫描(CT)结果评估为脑死亡的确证标准。为此,对14例符合脑死亡传统标准的患者进行了CT评估。14例患者中有7例(50%)出现了脑室系统严重受压或消失的CT表现,即所谓的“脑填塞”。增强CT,尤其是动态CT,只要脑血流得以保留,通常能清晰显示脑血管;相反,即使比较衰减值,脑结构缺乏强化也表明脑血流缺失。然而,10例患者中有7例(70%)出现了脑血管结构的强化,尤其是 Willis 环、大脑主要动脉、脉络丛和静脉窦。提示这一结果归因于CT显示能力的提高。CT在确证脑死亡中的作用在于可视化与脑死亡相关的病理变化,如“脑填塞”,以及缺乏强化对比表明脑血流缺失。后一点仍存在问题,因为血管造影显示在少数“脑死亡”患者中脑血流极低。建议通过动态CT扫描评估脑死亡时的脑血流,并与其他脑血流测定方法(如静脉数字减影血管造影)进行关联。

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