Nishiwaki H, Iriyama K, Kusaka N, Teranishi T, Mori H
Jpn J Surg. 1983 Nov;13(6):543-5. doi: 10.1007/BF02469501.
Hyper- and hypothermia was induced in dogs by peritoneal perfusion with warm or cold Lactate-Ringer's solution, the objective being to alter cardiac output. Changes in cardiac index, intravenous lipid clearance rate (K-value), and lipoprotein lipase (LPL) activity, concomitantly with changes of the temperature of the mixed venous blood were investigated. The cardiac index increased significantly with the hyperthermia and there was a close correlation between the cardiac index and the K-value. The LPL activity did not change significantly with changes in blood temperature, and the correlation between the LPL activity and the K-value was not significant. The hemodynamics has to be considered when attempting to discuss the intravenous lipid clearance rate.
通过向犬腹腔灌注温或冷的乳酸林格氏液诱导体温过高和过低，目的是改变心输出量。研究了心脏指数、静脉内脂质清除率（K值）和脂蛋白脂肪酶（LPL）活性的变化，以及混合静脉血温度的变化。体温过高时心脏指数显著增加，心脏指数与K值之间存在密切相关性。LPL活性并未随体温变化而显著改变，LPL活性与K值之间的相关性也不显著。在试图讨论静脉内脂质清除率时必须考虑血流动力学。
