Holzbauer M, Racké K, Sharman D F
Med Biol. 1983;61(5):258-63.
Dopamine (DA) was released from the isolated neural lobe of the pituitary gland by electrical stimulation of the pituitary stalk. This observation completes the evidence for DA to be classified as a neurotransmitter substance in the neural lobe in the rat hypophysis. From the experiments on the isolated neural lobe and simultaneous experiments on the combined neuro-intermediate lobe it could be calculated that the DA release from the intermediate lobe was about three times larger than that from the neural lobe. Electrical stimulation of the pituitary stalk in the presence of pargyline and TEA led to an increase in DA synthesis in the neural lobe. This effect did not occur in the intermediate lobe.
通过电刺激垂体柄，多巴胺（DA）从离体的垂体神经叶释放出来。这一观察结果完善了将DA归类为大鼠垂体神经叶神经递质物质的证据。根据对离体神经叶的实验以及对神经中间叶联合实验的同步实验，可以计算出中间叶释放的DA比神经叶释放的约大三倍。在存在优降宁和四乙铵的情况下电刺激垂体柄，会导致神经叶中DA合成增加。这种效应在中间叶中未出现。
