Benes F M, Swigar M E, Rothman S L, Opsahl C, Dowds M
Neurobiol Aging. 1983 Winter;4(4):289-95. doi: 10.1016/0197-4580(83)90005-2.
The CT scans of 50 elderly psychiatric patients were evaluated for the presence of discrete cerebral abnormalities. The prefrontal, superior temporal and inferior parietal areas showed the most frequent occurrence of defects. Motor, sensory and tertiary visual cortical regions, on the other hand, did not commonly exhibit signs of atrophy or sulcal widening. Clinical diagnoses of depression and dementia occurred in patients whether or not specific gyral defects were present, and therefore did not predict their presence. Patients with regional cerebral defects, however, were more likely to be older and to have sustained severe neurological insults. Patients with affective disorders who were treated with ECT showed no differences in the occurrence of superficial cerebral defects.
对50名老年精神病患者的CT扫描进行评估，以确定是否存在离散性脑异常。前额叶、颞上和顶下区域出现缺陷的频率最高。另一方面，运动、感觉和三级视觉皮质区域通常没有萎缩或脑沟增宽的迹象。无论是否存在特定的脑回缺陷，患者都有抑郁症和痴呆症的临床诊断，因此无法预测这些缺陷的存在。然而，有局部脑缺陷的患者年龄更大，并且遭受过严重的神经损伤。接受ECT治疗的情感障碍患者在浅表脑缺陷的发生率上没有差异。
