通过减少肾质量减轻大鼠实验性急性肾衰竭
Alleviation of experimental acute renal failure in rats by reduction of renal mass.
作者信息
Perez-Garcia R, Lopez-Novoa J M, Hernando L
出版信息
Biomedicine. 1978 Apr;29(2):43-4.
PMID:667285
Abstract
An acute renal failure (ARF) has been produced by glycerol injection on rats unilaterally nephrectomized 48 h before. Rats with reduced renal mass showed polyuria and significantly lower azotemia than controls with ARF. This data might be explained by increased glomerular plasma flow in the remnant kidney previous to ARF induction.
摘要
通过给48小时前进行单侧肾切除的大鼠注射甘油诱导出急性肾衰竭（ARF）。肾质量降低的大鼠出现多尿，且与急性肾衰竭对照组相比，氮质血症明显更低。该数据可能是由于在诱导急性肾衰竭之前残余肾的肾小球血浆流量增加所致。
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