Vila A, Chauplannaz G, Bady B
Rev Electroencephalogr Neurophysiol Clin. 1983 Dec;13(3):289-93. doi: 10.1016/s0370-4475(83)80040-9.
The authors tried to test the diagnostic yield of muscle and nerve biopsies in children and studied the relationships between clinical, electrophysiological and histopathological findings in 97 cases seen over a 3-year period. Specific histopathological lesions were described in 17.9% of muscle biopsies and 27.2% of nerve biopsies. In 65% of the cases, the biopsy revealed or confirmed the diagnosis, or specified the process (neurogenic or myogenic). Histopathology was concordant with clinical and electrophysiological findings in 83.5% of the cases.
作者试图测试肌肉和神经活检在儿童中的诊断价值,并研究了3年期间所见97例患者的临床、电生理和组织病理学结果之间的关系。在17.9%的肌肉活检和27.2%的神经活检中发现了特定的组织病理学病变。在65%的病例中,活检揭示或证实了诊断,或明确了病变过程(神经源性或肌源性)。在83.5%的病例中,组织病理学与临床和电生理结果一致。