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[红细胞滤过性及己酮可可碱治疗]

[Erythrocyte filterability and treatment with pentoxifylline].

作者信息

Valentini M, Sciannameo F, Francucci M, Tockner M, Sassano L, Allegra A

出版信息

Ric Clin Lab. 1983;13 Suppl 3:455-8.

PMID:6673029
Abstract

The purpose of our study was to verify the possibility of obtaining a reduction in the erythrocyte filtration rate and an improvement in the O2 tissue uptake in twenty patients suffering from insulin-dependent diabetes mellitus and diabetic angiopathy, randomly divided in two groups receiving pentoxifylline (1,200 mg/day for 30 days) or a placebo solution, respectively. The erythrocyte filtration rate decreased in patients treated with pentoxifylline and the difference of erythrocyte filtration rate between the two groups was statistically significant.

摘要

我们研究的目的是验证在20名患有胰岛素依赖型糖尿病和糖尿病性血管病变的患者中,降低红细胞滤过率以及改善组织对氧的摄取的可能性。这些患者被随机分为两组,分别接受己酮可可碱(1200毫克/天,共30天)或安慰剂溶液治疗。接受己酮可可碱治疗的患者红细胞滤过率降低,两组之间红细胞滤过率的差异具有统计学意义。

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