Giampalmo A, Berardi L, Martucciello G, Musso G L, Rossi F
Z Mikrosk Anat Forsch. 1983;97(5):785-96.
We have histochemically evaluated the LAP, AP and ANE activities of the human appendix in 100 surgical specimens. The mucosa has been particularly investigated for its different aspects during inflammatory conditions. Two main facts have been ascertained: the subepithelial location of macrophages, and the AP and ANE activities of two groups of cells in the germinal centers. Subepithelial macrophages show conspicuous AP activity that correlates with the degree of inflammatory response and of exposure to luminal antigens. In the germinal centers, AP and ANE activities disclose two further groups of positive cells, probably the same cells reacting to both technics. One group is rooted to the core of the germinal center; the other to the intermediate area between the germinal center and the follicular mantle.
我们已对100份手术标本中的人体阑尾进行了亮氨酸氨基肽酶（LAP）、碱性磷酸酶（AP）和α-萘酯酶（ANE）活性的组织化学评估。对黏膜在炎症状态下的不同方面进行了特别研究。已确定两个主要事实：巨噬细胞位于上皮下，生发中心有两组细胞具有AP和ANE活性。上皮下巨噬细胞显示出明显的AP活性，这与炎症反应程度和暴露于腔内抗原的情况相关。在生发中心，AP和ANE活性揭示了另外两组阳性细胞，可能是对两种技术均有反应的相同细胞。一组位于生发中心的核心；另一组位于生发中心与滤泡套之间的中间区域。
