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[热损伤后肾上腺髓质的超微结构及血儿茶酚胺水平]

[Ultrastructure of the adrenal medulla and blood catecholamine levels after exposure to thermal injury].

作者信息

Saakov B A, Bardakhch'ian E A

出版信息

Biull Eksp Biol Med. 1978 Jun;85(6):760-5.

PMID:667353
Abstract

A task was set to carry out electron microscope analysis of the adrenal gland medullary component and to compare with the biochemical data determinations of blood catecholamines during the burn shock. It was found that the response of the sympatho-adrenal system was phasic in character. During the erectile state of burn shock the elimination of adrenaline and noradrenaline took place, while during the torpid one further release of the granule content occurred exclusively on account of adrenaline. The distinctive moment of this period is intensification of the synthetic processes. It should be emphasized that the holocrine type of secretion prevailed after the burn, and just the latter led to the exhaustion of the adrenal medulla. Burn disease is characterized by processes coursing in the direction of restoration; however, catecholamine synthesis and secretion were less intensive than in healthy animals.

摘要

安排了一项任务,即对肾上腺髓质成分进行电子显微镜分析,并与烧伤休克期间血液中儿茶酚胺的生化数据测定结果进行比较。结果发现,交感 - 肾上腺系统的反应具有阶段性特征。在烧伤休克的勃起期,肾上腺素和去甲肾上腺素被清除,而在迟缓期,颗粒内容物的进一步释放仅由肾上腺素引起。这一时期的独特之处在于合成过程的强化。应该强调的是,烧伤后全质分泌类型占主导,正是后者导致了肾上腺髓质的耗尽。烧伤疾病的特征是朝着恢复方向发展的过程;然而,儿茶酚胺的合成和分泌比健康动物要弱。

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1
[Ultrastructure of the adrenal medulla and blood catecholamine levels after exposure to thermal injury].[热损伤后肾上腺髓质的超微结构及血儿茶酚胺水平]
Biull Eksp Biol Med. 1978 Jun;85(6):760-5.
2
No correlation between phaeochromocytoma catecholamine secretion and granule ultrastructure.嗜铬细胞瘤儿茶酚胺分泌与颗粒超微结构之间无相关性。
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Phaeochromocytoma, Electron microscopic study on catecholamine storage.嗜铬细胞瘤,儿茶酚胺储存的电子显微镜研究
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[Ultrastructural changes in the supraoptic nucleus and posterior lobe of the pituitary following experimental burns].[实验性烧伤后视上核及垂体后叶的超微结构变化]
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Effect of P286 on blood catecholamine levels and survival rate in dogs exposed to hemorrhagic shock.P286对失血性休克犬血液儿茶酚胺水平及存活率的影响。
Arch Int Pharmacodyn Ther. 1968 Jul;174(1):167-80.