Lundberg M, Erlanson P, Larsson R
Scand J Urol Nephrol. 1977;11(1):47-51. doi: 10.3109/00365597709179691.
Quinton-Scribner shunts have been used as a reliable access to the blood-stream in 56 patients treated with intermittent hemodialysis in the years 1965-71. The mean age of 29 men and 27 women was 39 years. Two hundred and thirty-two cannulae showed a mean survival time of 11.2 months for 103 arterial cannulae and 9.0 months for 129 venous cannulae. 700 shunt clotting episodes occurred during 1157 patient months, i.e. 0.6 clotting episode/month. In 350 episodes where saline flushing could not remove the clot, the effect of treatment with streptokinase was considered evident in 79.7%. Shunt cannula infection was a common complication while aseptic cutaneous necrosis and bleeding from the cannulated vessel were seen less frequently. Both severe and less harmful bleeding episodes were seen as a complication of dicumarol therapy. The number of complications to streptokinase treatments was low. The advantages and disadvantages of the Quinton-Scribner shunt for hemodialysis are discussed.
1965年至1971年间，56例接受间歇性血液透析治疗的患者使用了昆顿-斯克里布纳分流管作为可靠的血液通路。29名男性和27名女性的平均年龄为39岁。232根套管显示，103根动脉套管的平均存活时间为11.2个月，129根静脉套管的平均存活时间为9.0个月。在1157个患者月期间发生了700次分流管凝血事件，即每月0.6次凝血事件。在350次生理盐水冲洗无法清除血栓的事件中，链激酶治疗的效果在79.7%的事件中被认为是明显的。分流管套管感染是常见的并发症，而无菌性皮肤坏死和插管血管出血则较少见。严重和危害较小的出血事件均被视为双香豆素治疗的并发症。链激酶治疗的并发症数量较少。文中讨论了昆顿-斯克里布纳分流管用于血液透析的优缺点。
