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[弥漫性毒性甲状腺肿的药物治疗。长期功能结果(302例)]

[Drug therapy of Basedow's disease. Long term functional results (302 cases)].

作者信息

Scazziga B R

出版信息

Schweiz Med Wochenschr. 1977 Apr 2;107(13):423-7.

PMID:66747
Abstract

302 cases of Graves' disease were treated with a single course of antithyroid drugs and followed during 2 to 15 years. 71% of the patients showed a prolonged remission, 27,1% recurred and 1.9% were hypothyroid. Considering the yearly incidence of the recurrencies, the risk of a recurrency estimated 14 years after the treatment was 35% (cumulative incidence). Among the factors studied, hyperthyroidism of short duration seemed to correlate with a prolonged remission.

摘要

302例格雷夫斯病患者接受了一个疗程的抗甲状腺药物治疗,并随访了2至15年。71%的患者获得了长期缓解,27.1%复发,1.9%出现甲状腺功能减退。考虑到复发的年发生率,治疗后14年估计的复发风险为35%(累积发生率)。在所研究的因素中,病程短的甲状腺功能亢进似乎与长期缓解相关。

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