Pichlmayr I, Lips U
Neuropsychobiology. 1983;10(4):239-48. doi: 10.1159/000118018.
Knowledge of the actual state of cerebral function and of the changes induced by psychotropic drugs is important not only to neurologically oriented specialties but also to other branches of medicine concerned with altering cerebral function. This applies especially to anesthesiology which involves numerous procedures leading to a temporary loss of cognitive brain function. Recently, the application of EEG combined with spectral analysis performed during anesthesia and intensive-care treatment has attracted attention: we investigated the changes in EEG during standardized anesthesiological and therapeutical procedures pre-, intra- and postoperatively, or during intensive-care treatment in 1,500 patients undergoing general surgery from 1977 to 1982. Two-track EEG leads accompanied by spectral analysis were used on line. The evaluation of routinely applied EEG monitoring justifies the following statements: EEG monitoring can be adapted technically and organized to comply with the working conditions and daily activities of an anesthesiological department. Spectral analytic representations allow the assessment of the EEG by the anesthesiologist. The various methods of general anesthesia produce specific EEG changes which can be obliterated by the cumulative effect of drugs. The actual depth of anesthesia is visible in the EEG. During a defined constant anesthetic depth, potentially hazardous cerebral dysfunctions can be detected early and treated accordingly. EEG monitoring can be useful in solving urgent medical problems of intensive-care therapy.
了解大脑功能的实际状态以及精神药物所引起的变化,不仅对以神经学为导向的专业领域很重要,而且对涉及改变大脑功能的其他医学分支也很重要。这尤其适用于麻醉学,因为麻醉学涉及众多导致大脑认知功能暂时丧失的操作。最近,脑电图(EEG)结合在麻醉和重症监护治疗期间进行的频谱分析的应用引起了关注:我们调查了1977年至1982年间1500例接受普通外科手术患者在标准化麻醉和治疗程序术前、术中和术后,或在重症监护治疗期间脑电图的变化。使用双道脑电图导联并在线进行频谱分析。对常规应用的脑电图监测的评估证明了以下几点:脑电图监测在技术上可以调整并进行组织,以符合麻醉科的工作条件和日常活动。频谱分析表示法使麻醉医生能够评估脑电图。各种全身麻醉方法会产生特定的脑电图变化,这些变化可能会被药物的累积作用消除。麻醉的实际深度在脑电图中可见。在确定的恒定麻醉深度下,可以早期检测到潜在危险的大脑功能障碍并进行相应治疗。脑电图监测有助于解决重症监护治疗中的紧急医疗问题。