Watanabe K, Morikawa M, Hayashi M, Hayashi S, Hosokawa O, Yamazoe M, Yazawa Y, Shibata A, Eguchi S, Matsukawa T
J Cardiogr. 1983 Dec;13(4):959-66.
Cardiac function and left ventricular regional wall motion were examined using two-dimensional echocardiography in 40 post-operative patients of tetralogy of Fallot (TOF) of an average of 13 years after the correction. From the data of treadmill exercise test and cardiac catheterization, patients were classified into two groups; cases with complete ability for treadmill test (Group A, n = 22), and disabled for the test and the right ventricular systolic pressure above 50 mmHg (Group B, n = 18). Compared with the control group (n = 10), the patient groups had greater cardiothoracic ratios (CTR) and right/left ventricular dimensions (RVd/LVd) (p less than 0.001), and Group B had a greater CTR and RVd/LVd than Group A (respectively p less than 0.001). Compared with the control group, the patient groups had no significant differences in corrected ejection time, fractional shortening and mean velocity of circumferential fiber shortening, and no difference was noted between Group A and Group B. Left ventricular regional wall was divided into 12 segments around the left ventricular circumference on the two-dimensional short-axis view and the regional wall motion was evaluated on the basis of [(diastolic-systolic)/diastolic left hemiaxial length X 100%] values. In Group B, akinetic or dyskinetic wall motion was visualized at the interventricular septum and left ventricular posterior wall, but there was no abnormal motion in the control group and Group A. We concluded that even in postoperative patients with preserved cardiac function at rest, some of them had abnormal left ventricular regional wall motion due to the persistent right ventricular overload or corrective patch, resulting in low exercise capacity.
对40例法洛四联症(TOF)术后平均13年的患者,采用二维超声心动图检查心脏功能和左心室局部室壁运动。根据平板运动试验和心导管检查数据,将患者分为两组:平板试验能力完全正常的病例(A组,n = 22),以及试验功能障碍且右心室收缩压高于50 mmHg的病例(B组,n = 18)。与对照组(n = 10)相比,患者组的心胸比率(CTR)和右/左心室尺寸(RVd/LVd)更大(p < 0.001),且B组的CTR和RVd/LVd比A组更大(分别为p < 0.001)。与对照组相比,患者组在校正射血时间、缩短分数和圆周纤维缩短平均速度方面无显著差异,A组和B组之间也无差异。在二维短轴视图上,将左心室局部室壁沿左心室圆周分为12段,并根据[(舒张末期 - 收缩末期)/舒张末期左半轴长度×100%]值评估局部室壁运动。在B组中,室间隔和左心室后壁可见运动减弱或运动障碍,但对照组和A组未发现异常运动。我们得出结论,即使在静息时心脏功能保留的术后患者中,部分患者仍因持续性右心室负荷过重或矫正补片而出现左心室局部室壁运动异常,导致运动能力低下。