蝎子黄肥尾蝎毒液的溶血作用。
Haemolytic effect of the scorpion Heterometrus fulvipes venom.
作者信息
Venkaiah B, Parthasarathy P R, Krishnaswamy S
出版信息
Biochem Int. 1983 Aug;7(2):241-5.
PMID:6679342
Abstract
The haemolytic effect of the venom from scorpion Heterometrus fulvipes was studied using sheep erythrocytes. While there was no haemolytic effect seen directly by the erythrocytes, erythrocytes sensitized with homologous haemolysin were lysed by the venom. This factor in Heterometrus fulvipes venom having a 'complement like' haemolytic effect was found to be thermolabile and dialysable and sensitive to the action of 2-mercaptoethanol. It was identified as a low molecular weight peptide containing disulphide groups.
摘要
利用绵羊红细胞研究了黄肥尾蝎毒液的溶血作用。虽然红细胞未直接观察到溶血作用，但用同源溶血素致敏的红细胞被该毒液溶解。发现黄肥尾蝎毒液中具有“补体样”溶血作用的这一因子对热不稳定、可透析，且对2-巯基乙醇的作用敏感。它被鉴定为一种含二硫键的低分子量肽。
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