Healy D L, Bacher J, Hodgen G D
J Med Primatol. 1983;12(2):89-100.
The aim of this study was to develop an operation for total thymectomy suitable for nonhuman primates. The thymus was removed from 24 macaque monkeys from fetal to adult life by a cervicothoracotomy and blunt gauze dissection. Mean wet weight of the thymus rose from 150 mg (range 50-250 mg) in fetal animals to 2.5 gm (range 0.3-4.2 gm) in prepubertal monkeys. Nonhuman primate thymic weight fell steadily and uniformly with age by over 300% when plotted as a function of body weight. This surgical technique appears to be a valid method of total thymectomy in macaque monkeys.
本研究的目的是开发一种适用于非人灵长类动物的全胸腺切除术。通过颈胸切开术和钝性纱布分离法，从24只从胎儿期到成年期的猕猴身上摘除胸腺。胸腺的平均湿重从胎儿期动物的150毫克（范围为50 - 250毫克）增加到青春期前猴子的2.5克（范围为0.3 - 4.2克）。当将非人灵长类动物的胸腺重量作为体重的函数绘制时，其随年龄稳步且均匀下降超过300%。这种手术技术似乎是猕猴全胸腺切除术的一种有效方法。
