Boenning D A, Fleisher G R, Campos J M
Am J Emerg Med. 1983 Jul;1(1):17-21. doi: 10.1016/0735-6757(83)90032-3.
Fifty-five children with nonfacial dog bites were prospectively studied. Patients were assigned to an experimental group receiving oral penicillin or a control group receiving local wound care only. Wounds were cultured for anaerobic and aerobic flora prior to cleansing. Results showed that most children were bitten on an extremity by a familiar dog, sustained simple injuries, and sought prompt medical attention. The overall infection rate was 3.6%, with one patient in each group developing an infection. The most frequently recovered organisms were normal skin flora. No Pasteurella multocida were isolated. Forty percent of cultures yielded potential pathogens. Despite this finding, initial cultures of dog bite wounds had no value in predicting subsequent infection. This study suggests that routine use of prophylactic penicillin is not required for simple nonfacial dog bites in children.
对55名非面部被狗咬伤的儿童进行了前瞻性研究。患者被分为接受口服青霉素的实验组或仅接受局部伤口护理的对照组。在清洗伤口之前,对伤口进行了厌氧和需氧菌群培养。结果显示,大多数儿童是被熟悉的狗咬伤了四肢,受伤情况简单,且能及时就医。总体感染率为3.6%,每组各有一名患者发生感染。最常分离出的微生物是正常皮肤菌群。未分离到多杀巴斯德菌。40%的培养物培养出潜在病原体。尽管有这一发现,但狗咬伤伤口的初始培养对预测后续感染并无价值。这项研究表明,对于儿童简单的非面部狗咬伤,无需常规使用预防性青霉素。