Gibertoni M, Bonito V, Colombo A, Falasca A, Nichelli P
Riv Patol Nerv Ment. 1983 Jul-Aug;104(4):179-83.
A 64 year-old man, who had been ingesting 20 g of licorice daily for about five months, developed a progressive, diffuse muscle weakness, with myoglobinuria, severe hypokalemia and elevated serum muscle enzymes. Electromyography and muscle biopsy results were consistent with a necrotizing myopathy. Following licorice withdrawal and appropriate electrolyte administration, complete clinical recovery was observed within about ten days. Previous reports of similar cases are reviewed and causative factors of this kind of myopathy are discussed.
一名64岁男性，连续约五个月每天摄入20克甘草，出现进行性弥漫性肌肉无力，并伴有肌红蛋白尿、严重低钾血症和血清肌肉酶升高。肌电图和肌肉活检结果与坏死性肌病相符。停用甘草并给予适当的电解质补充后，约十天内观察到临床完全恢复。本文回顾了既往类似病例的报告，并讨论了这种肌病的致病因素。
