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[上尿路尿路上皮肿瘤的临床研究。1:原发性肾盂肿瘤]

[Clinical study of urothelial tumors of the upper urinary tract. 1: Primary renal pelvic tumors].

作者信息

Hiramatsu T, Ijuin M, Hirao Y, Ohara S, Shiomi T, Babaya K, Hijioka T, Hashimoto M, Maruyama Y, Suemori T

出版信息

Hinyokika Kiyo. 1983 Oct;29(10):1191-204.

PMID:6681497
Abstract

Forty primary renal pelvic tumors treated at our University between 1963 and 1981, were reviewed retrospectively. The conclusions of this study are as follows. Sex and age distribution of the patients were 30 males and 10 females (3: 1), and average age was 60.5 years old. The major symptoms were hematuria and flank pain; however, palpable mass was rare. The majority of patients were admitted to our clinic within 6 months from manifestation of symptoms. The major findings of IVP were non-functioning kidney and filling defect. The positive rate of urinary cytology was 46.7%. Total nephroureterectomy with bladder cuff was performed in 20 out of 32 cases. Histologically, 29 cases were transitional cell carcinoma and 4 cases were squamous cell carcinoma with renal calculi. Simultaneous urothelial tumors were seen in 10 cases, 3 in the ureter and 7 in the bladder. A subsequent ureteral tumor was found in one out of 12 cases in which ureters were resected incompletely, and 7 subsequent bladder tumors were found out of 32 cases receiving surgical treatment in the follow-up period. The 5-year survival rate by the actuarial method was 75.9%. Among several factors, grade and stage of the tumor were the most influencing factors for prognosis. An effective method of post-operative treatment could not be established.

摘要

回顾性分析了1963年至1981年在我校接受治疗的40例原发性肾盂肿瘤。本研究的结论如下。患者的性别和年龄分布为男性30例,女性10例(3:1),平均年龄为60.5岁。主要症状为血尿和侧腹痛;然而,可触及肿块罕见。大多数患者在症状出现后6个月内入院。静脉肾盂造影的主要表现为患肾无功能和充盈缺损。尿细胞学检查阳性率为46.7%。32例患者中有20例行全肾输尿管切除术并切除膀胱袖状组织。组织学检查,29例为移行细胞癌,4例为伴有肾结石的鳞状细胞癌。同时性尿路上皮肿瘤10例,输尿管3例,膀胱7例。在输尿管切除不完全的12例患者中,有1例发现了随后的输尿管肿瘤,在随访期接受手术治疗的32例患者中,有7例发现了随后的膀胱肿瘤。采用精算方法计算的5年生存率为75.9%。在几个因素中,肿瘤的分级和分期是对预后影响最大的因素。尚未确立有效的术后治疗方法。

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1
[Clinical study of urothelial tumors of the upper urinary tract. 1: Primary renal pelvic tumors].[上尿路尿路上皮肿瘤的临床研究。1:原发性肾盂肿瘤]
Hinyokika Kiyo. 1983 Oct;29(10):1191-204.
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[Clinical study of urothelial tumors of the upper urinary tract. 2: Primary ureteral tumors].
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