Wright P J, Stelmasiak T, Anderson G A
J Reprod Fertil. 1983 Jan;67(1):197-202. doi: 10.1530/jrf.0.0670197.
The patterns of LH release were studied in 5 ewes, ovariectomized when 3 days post partum, at 4, 14, 33, 47 and 61 days after ovariectomy. These patterns were compared with those in 4 seasonally anoestrous (control) ewes ovariectomized and sampled at the same times. In the control ewes regular pulsatile release of LH was apparent 4 days after ovariectomy: plasma LH concentrations and LH pulse frequencies, but not pulse amplitudes, then declined. In the post-partum ewes all indices of LH release were lower than those in the control ewes at 4 days after ovariectomy, but then they increased: pulse amplitude was greater (P less than 0.05) at 14 days after ovariectomy, and plasma LH concentrations were greater (P less than 0.05, 0.01) at 14 and 33 days than in control ewes. These results indicate that the hypothalamopituitary axis of lactating ewes has a reduced capacity to release LH for only a short period after ovariectomy early in the post-partum period. This probably reflects the time needed for recovery from the inhibitory effects of ovarian and placental hormones, and may reflect reduced secretion of LH-RH.
对5只产后3天卵巢被切除的母羊在卵巢切除后4、14、33、47和61天的促黄体生成素（LH）释放模式进行了研究。将这些模式与4只在相同时间进行卵巢切除和取样的季节性乏情（对照）母羊的模式进行了比较。在对照母羊中，卵巢切除后4天促黄体生成素的规律性脉冲式释放很明显：血浆促黄体生成素浓度和促黄体生成素脉冲频率随后下降，但脉冲幅度未下降。在产后母羊中，卵巢切除后4天促黄体生成素释放的所有指标均低于对照母羊，但随后它们有所增加：卵巢切除后14天脉冲幅度更大（P<0.05），14天和33天血浆促黄体生成素浓度高于对照母羊（P<0.05，0.01）。这些结果表明，在产后早期卵巢切除后的短时间内，泌乳母羊的下丘脑-垂体轴释放促黄体生成素的能力降低。这可能反映了从卵巢和胎盘激素的抑制作用中恢复所需的时间，也可能反映了促性腺激素释放激素（LH-RH）分泌的减少。
