Cressent M, Elie C, Taboulet J, Moukhtar M S, Milhaud G
Proc Soc Exp Biol Med. 1983 Feb;172(2):158-62. doi: 10.3181/00379727-172-41539.
Plasma levels of calcium (Ca), phosphate (P), calcitonin (CT), parathyroid hormone (PTH), and prolactin (PRL) were measured at 8, 13, and 17 hr during the 4-day estrous cycle of the rat. Ca levels fell throughout the day during proestrus (PE) and estrus (E). In contrast Ca rose transiently during diestrus (D1, D2). P levels fluctuated inconsistently at all stages of the cycle with the exception of E where P levels were significantly higher at 13 hr. CT levels showed an increase during D1 and D2 and fell to their lowest values during E, at 13 hr. Daily fluctuations in each stage were also recorded. Variations of PTH levels during the estrous cycle were minor. PRL levels increased sharply during PE. No direct relationship between PRL secretion and CT secretion could be established. These results indicate that CT but not PTH varies specifically in relation to the estrous cycle. They suggest that there is a link between sexual hormones and CT, apparently independent of plasma calcium levels.
在大鼠4天发情周期的第8、13和17小时测量血浆钙（Ca）、磷（P）、降钙素（CT）、甲状旁腺激素（PTH）和催乳素（PRL）水平。在发情前期（PE）和发情期（E），钙水平全天下降。相比之下，在动情间期（D1、D2）钙水平短暂升高。除发情期13小时磷水平显著升高外，磷水平在周期的所有阶段波动不一致。降钙素水平在D1和D2期间升高，在发情期13小时降至最低值。还记录了每个阶段的每日波动情况。发情周期中甲状旁腺激素水平的变化较小。催乳素水平在发情前期急剧升高。无法确定催乳素分泌与降钙素分泌之间存在直接关系。这些结果表明，降钙素而非甲状旁腺激素随发情周期有特异性变化。它们表明性激素与降钙素之间存在联系，显然独立于血浆钙水平。
