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哺乳动物视网膜色素上皮中的髓样小体。

Myeloid bodies in the mammalian retinal pigment epithelium.

作者信息

Tabor G A, Fisher S K

出版信息

Invest Ophthalmol Vis Sci. 1983 Mar;24(3):388-91.

PMID:6682095
Abstract

In the retinal pigment epithelium (RPE) of a mammal, the Eastern gray squirrel, a type of cytoplasmic organelle, the so-called "myeloid body" that was previously thought to be restricted to the RPE of lower vertebrates was observed. In the squirrel, these organelles are continuous with the smooth endoplasmic reticulum (SER), lack an enclosing membrane, and in general exhibit all the morphologic criteria used to identify myeloid bodies. The presumptive myeloid bodies in the squirrel RPE are most prevalent in animals killed during the early hours of the dark period of a 12L:12D lighting cycle. They are rarely observed in animals killed just prior to or during the light period. Thus, these findings document for the first time the occurrence of myeloid bodies in the mammalian RPE, and indicate that their presence is influenced by a diurnal lighting cycle.

摘要

在哺乳动物东部灰松鼠的视网膜色素上皮(RPE)中,观察到一种细胞质细胞器,即所谓的“髓样小体”,这种小体以前被认为只存在于低等脊椎动物的RPE中。在松鼠中,这些细胞器与光滑内质网(SER)相连,没有封闭膜,并且总体上呈现出用于识别髓样小体的所有形态学标准。松鼠RPE中的推定髓样小体在12小时光照:12小时黑暗光照周期的黑暗期早期被杀死的动物中最为普遍。在紧接光照期之前或光照期期间被杀死的动物中很少观察到它们。因此,这些发现首次记录了哺乳动物RPE中髓样小体的存在,并表明它们的存在受昼夜光照周期的影响。

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