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[急性溴隐亭负荷对各种神经内分泌疾病患者催乳素和生长激素含量的影响]

[Effect of acute parlodel load on the prolactin and STH content in patients with various neuroendocrine diseases].

作者信息

Mel'nichenko G A, Bol'shakova T D, Gitel' E P, Langner T K, Barkova M V

出版信息

Probl Endokrinol (Mosk). 1983 Jan-Feb;29(1):19-23.

PMID:6682222
Abstract

The results are presented of the treatment of 31 females with different hypothalamic-hypophyseal abnormalities: persisting lactorrhea-amenorrhea syndrome, acromegaly, hypothalamic syndrome, lactorrhea syndrome without amenorrhea. The effect of parlodel acute load on STH and the blood serum prolactin content was studied. It was concluded, that parlodel acute load produces a marked decrease in the prolactin level 2 hours after the drug injection both in the patients with an originally elevated prolactin level, and in the subjects, having the prolactin level within normal. Significant changes in the STH level were not observed 2 hours after parlodel load.

摘要

本文呈现了对31例患有不同下丘脑 - 垂体异常的女性患者的治疗结果,这些异常包括持续性溢乳 - 闭经综合征、肢端肥大症、下丘脑综合征、无闭经的溢乳综合征。研究了溴隐亭急性负荷对生长激素(STH)和血清催乳素含量的影响。得出的结论是,无论是初始催乳素水平升高的患者,还是催乳素水平在正常范围内的受试者,在注射药物后2小时,溴隐亭急性负荷都会使催乳素水平显著降低。在溴隐亭负荷后2小时,未观察到生长激素水平有显著变化。

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