Küenzlen E, Bauer J, Behringhoff B, Ettinger J, Mueller-Eckhardt C
Dtsch Med Wochenschr. 1983 Apr 29;108(17):651-4. doi: 10.1055/s-2008-1069614.
Thrombocytopenic purpura occurred in two women aged 67 and 77 years, who earlier on had been pregnant, six and twelve days after blood transfusions. The platelet deficient phase lasted 16 and more than 50 days. Differentiation from other causes of thrombocytopenic haemorrhage was based on immunohaematologic findings. Both patients were negative for the platelet specific antigen PlA1 (Zwa). The platelet specific antibody (anti-PlA1) responsible for the purpura could be demonstrated and characterised immunologically.
两名分别为67岁和77岁的女性在输血后6天和12天出现血小板减少性紫癜,她们此前都曾怀孕。血小板缺乏期持续了16天和超过50天。与血小板减少性出血的其他原因的鉴别基于免疫血液学检查结果。两名患者的血小板特异性抗原PlA1(Zwa)均为阴性。导致紫癜的血小板特异性抗体(抗PlA1)可以通过免疫学方法得到证实和鉴定。