六氯铱酸钠对小鼠腹水瘤的杀瘤作用。
Tumoricidal effects of sodium hexachloroiridate on an ascitic tumor in mice.
作者信息
Kolodny G M, Rose C
出版信息
Cancer Res. 1983 Jul;43(7):3101-3.
PMID:6682698
Abstract
Sodium hexachloroiridate injected 1 day after i.p. injection of 10(6) mouse ovarian tumor cells prevents the appearance of ascitic tumors in mice. Mice given injections of tumor cells all die at 20 to 30 days after tumor injection. Mice treated with sodium hexachloroiridate after tumor injection either have significant prolongation of life span without ascites or show no evidence of cancer even up to 7 months after tumor injection.
摘要
在腹腔注射10⁶个小鼠卵巢肿瘤细胞1天后注射六氯铱酸钠，可防止小鼠出现腹水瘤。注射肿瘤细胞的小鼠在肿瘤注射后20至30天全部死亡。肿瘤注射后用六氯铱酸钠治疗的小鼠，要么寿命显著延长且无腹水，要么在肿瘤注射后长达7个月都没有癌症迹象。
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