Janson P O, Williams D, Petrucco O M, Amato F, Seamark R F, Findlay J K
Acta Endocrinol (Copenh). 1983 Jun;103(2):259-65. doi: 10.1530/acta.0.1030259.
Blood flow of the ovary, vascular pedicle and oviduct was measured in anaesthetized non-cycling and cycling ewes by timed collection of ovarian venous blood. The degree of arterio-venous shunting across the ovary and pedicle was estimated both in vivo and in vitro by perfusing the tissues with 15 +/- 5 micrometers radioactive microspheres. The mean ovarian blood flow in non-cycling animals was 1.9 ml/min, which was 51% of blood flow in the ovarian vein. In cycling animals ovarian blood flow at midcycle was 2.9 ml/min (66% of ovarian venous flow) in non-luteal ovaries and 4.3 ml/min (79% of venous flow) in luteal ovaries. The degree of arterio-venous shunting was low in all stages of the cycle (1.0-2.6% across ovary + pedicle). The degree of shunting was also found to be very small in vitro (0.007-1.38%) in both non-luteal and luteal ovaries. A considerable number of microspheres was entrapped in the vascular pedicle of the ovary indicating the presence of an extensive capillary bed. There was an inverse relationship between blood flow in the ovary and flow in the vascular pedicle. Alterations in distribution of blood flow between the ovary and adjacent structures supplied by the ovarian artery may be of functional significance in allowing rapid changes in ovarian blood flow. The results of the present study indicate that changes in ovarian blood flow during the oestrus cycle are not caused by an action on arterio-venous shunt vessels.
通过定时采集卵巢静脉血，对麻醉状态下非发情周期和发情周期的母羊的卵巢、血管蒂和输卵管的血流量进行了测量。通过用15±5微米的放射性微球灌注组织，在体内和体外估计了穿过卵巢和蒂的动静脉分流程度。非发情周期动物的平均卵巢血流量为1.9毫升/分钟，占卵巢静脉血流量的51%。在发情周期的动物中，非黄体期卵巢在周期中期的血流量为2.9毫升/分钟（占卵巢静脉血流量的66%），黄体期卵巢为4.3毫升/分钟（占静脉血流量的79%）。在周期的所有阶段，动静脉分流程度都很低（穿过卵巢+蒂为1.0 - 2.6%）。在非黄体期和黄体期卵巢的体外实验中也发现分流程度非常小（0.007 - 1.38%）。相当数量的微球被困在卵巢的血管蒂中，表明存在广泛的毛细血管床。卵巢血流量与血管蒂血流量之间呈负相关。卵巢动脉供应的卵巢与相邻结构之间血流分布的改变，对于允许卵巢血流量快速变化可能具有功能意义。本研究结果表明，发情周期中卵巢血流量的变化不是由对动静脉分流血管的作用引起的。
