Obeso J A, Rothwell J C, Lang A E, Marsden C D
Neurology. 1983 Jul;33(7):825-30. doi: 10.1212/wnl.33.7.825.
We studied 14 patients who had a combination of idiopathic torsion dystonia and myoclonic jerks. In many cases, the same muscles were involved in both the myoclonus and the dystonia. This made observation of the crucial dystonic postures difficult and led to misdiagnosis of other dyskinesias. The jerks usually were brief (50 to 200 msec) and occurred irregularly, often showing cocontraction in antagonist muscles. Frequently, they were superimposed upon sustained dystonic contractions in the same or distant muscles. We found no time-locked EEG event before the jerks. The myoclonus probably arises from a subcortical focus, and the visible jerks probably are part of the spectrum of involuntary movements that accompany torsion dystonia.
我们研究了14例患有特发性扭转性肌张力障碍合并肌阵挛性抽搐的患者。在许多病例中，肌阵挛和肌张力障碍累及相同的肌肉。这使得观察关键的肌张力障碍姿势变得困难，并导致对其他运动障碍的误诊。抽搐通常很短暂（50至200毫秒）且发作不规则，常表现为拮抗肌的共同收缩。它们经常叠加在同一或远处肌肉的持续性肌张力障碍性收缩之上。我们在抽搐之前未发现与时间锁定的脑电图事件。肌阵挛可能起源于皮质下病灶，而可见的抽搐可能是扭转性肌张力障碍伴随的不自主运动谱的一部分。
