类风湿关节炎患者青霉胺治疗期间发生血栓性血小板减少性紫癜。
Thrombotic thrombocytopenic purpura during penicillamine therapy in rheumatoid arthritis.
作者信息
Trice J M, Pinals R S, Plitman G I
出版信息
Arch Intern Med. 1983 Jul;143(7):1487-8.
PMID:6683487
Abstract
Thrombotic thrombocytopenic purpura (TTP) developed in a patient with seropositive rheumatoid arthritis (RA) after 2 1/2 months of treatment with penicillamine. After discontinuation of the drug, plasmapheresis and steroid therapy led to a sustained remission. To our knowledge, no prior cases of penicillamine-induced TTP in RA have been reported.
摘要
一名血清阳性类风湿关节炎（RA）患者在接受青霉胺治疗2个半月后发生血栓性血小板减少性紫癜（TTP）。停用该药物后，血浆置换和类固醇治疗使其持续缓解。据我们所知，此前尚无RA患者发生青霉胺诱导的TTP的病例报道。
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