Gepner-Woźniewska M, Sitarska E, Kluciński W, Konopka L, Roszkowski S
Acta Haematol Pol. 1977 Jan-Mar;8(1):21-7.
In 100 patients with various haematological syndromes and in 22 healthy subjects serum transferrin was determined by the method of radial immunodiffusion of Mancini. The results were correlated with total iron-binding capacity, iron concentration, beta1 globulin and albumin levels. A statistically significant rise in serum transferrin concentration was demonstrated only in patients with sideropenic anaemia. In the remaining groups of patients transferrin concentration was decreased without regard to associated disturbances of iron metabolism and iron level. The comparison of the total iron-binding capacity with transferrin level determined by radial immunodiffusion may suggest presence of iron-binding proteins other than transferrin.
采用曼西尼放射免疫扩散法测定了100例各种血液学综合征患者和22名健康受试者的血清转铁蛋白。将结果与总铁结合力、铁浓度、β1球蛋白和白蛋白水平进行相关性分析。仅在缺铁性贫血患者中血清转铁蛋白浓度有统计学意义的升高。在其余几组患者中,转铁蛋白浓度降低,而与铁代谢和铁水平的相关紊乱无关。通过放射免疫扩散法测定的总铁结合力与转铁蛋白水平的比较可能提示存在除转铁蛋白之外的铁结合蛋白。