Winter M, Needham J, Barkhan P
Haemostasis. 1983;13(2):83-8. doi: 10.1159/000214708.
A patient with a lifelong bleeding tendency of moderate severity was found to have both factor XI deficiency and a long bleeding time. There was a significant deficiency of platelet factor 3, but other parameters of platelet function were normal. Infusion studies showed that both fresh plasma and platelet concentrate were required for complete correction of the haemostatic abnormalities, suggesting that these two defects were inherited coincidentally.
一名患有中度严重程度终身出血倾向的患者被发现同时存在因子XI缺乏和出血时间延长的情况。血小板因子3严重缺乏，但血小板功能的其他参数正常。输注研究表明，新鲜血浆和血小板浓缩物都需要用于完全纠正止血异常，这表明这两种缺陷是巧合遗传的。
