Liedholm P, Sjöberg N O, Srivastava K, Astedt B
Contraception. 1978 Jun;17(6):531-3.
An increase in menstrual blood loss is one of the most common side effects of plastic IUDs and, though less often, also of copper IUDs. This has been explained by the observation that IUD enhances the fibrinolytic activity of the endometrium. A progesterone-releasing IUD (ProgestasertR) does not increase menstrual bleeding. The fibrinolytic activity of the endometrium was studied in 17 women before and after insertion of a progesterone-releasing IUD. It did not enhance the histochemically determined fibrinolytic activity in the endometrium.
月经量增加是塑料宫内节育器最常见的副作用之一,铜质宫内节育器较少出现这种情况。据观察,宫内节育器会增强子宫内膜的纤溶活性,对此现象已有相关解释。含孕酮宫内节育器(ProgestasertR)不会增加月经量。研究人员对17名女性在放置含孕酮宫内节育器前后的子宫内膜纤溶活性进行了研究。结果显示,该节育器并未增强子宫内膜组织化学测定的纤溶活性。