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[小鼠品系及其杂种的神经学特征(兴奋阈值)与行为特征之间的遗传关系]

[Genetic relationship between the neurological (excitability thresholds) and the behavioral characteristics of mouse strains and their hybrids].

作者信息

Dmitriev Iu S

出版信息

Genetika. 1983 Jun;19(6):958-64.

PMID:6684075
Abstract

The comparative genetic analysis of 16 inbred mouse strains was carried out for excitability thresholds of peripherical parts of the nervous system, viability to learning, short-term memory and exploratory activity in different experimental conditions. The high positive correlation was shown between excitability thresholds of different parts of the peripherical nervous system, the high negative correlation being established between excitability thresholds, viability to learning, short-term memory and exploratory activity. The data led to the conclusion about the existence of the pleiotropic effect of genes controlling the excitability thresholds, on peculiarities of behaviour. This was confirmed by the findings obtained in the study of various hybrids, which point to the similar way of inheritance of excitability thresholds and behavioural patterns.

摘要

对16个近交系小鼠品系进行了比较遗传分析,以研究不同实验条件下神经系统外周部分的兴奋性阈值、学习生存能力、短期记忆和探索活动。结果表明,外周神经系统不同部位的兴奋性阈值之间存在高度正相关,而兴奋性阈值、学习生存能力、短期记忆和探索活动之间则存在高度负相关。这些数据得出结论,控制兴奋性阈值的基因对行为特征存在多效性影响。对各种杂种的研究结果证实了这一点,这些结果表明兴奋性阈值和行为模式的遗传方式相似。

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[Genetic relationship between the neurological (excitability thresholds) and the behavioral characteristics of mouse strains and their hybrids].[小鼠品系及其杂种的神经学特征(兴奋阈值)与行为特征之间的遗传关系]
Genetika. 1983 Jun;19(6):958-64.
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