Ehlers C L, Indik J H, Koob G F, Bloom F E
Prog Neuropsychopharmacol Biol Psychiatry. 1983;7(2-3):217-22. doi: 10.1016/0278-5846(83)90110-0.
Locomotor activity following administration of apomorphine (0.1 mg/kg), and amphetamine (1 mg/kg) was studied in rats receiving single and multiple electroconvulsive shock (ECS). Three groups of rats were utilized, one half of each group received sham treatment and the other half received either 1,5, or 10 daily ECS. Significant enhancement of the locomotor response to amphetamine, but not apomorphine, was seen in rats given repeated ECS as compared to controls. This study suggests that the number of ECS, is an important variable in ECS enhancement of locomotor response to amphetamine.
在接受单次和多次电惊厥休克（ECS）的大鼠中，研究了给予阿扑吗啡（0.1毫克/千克）和苯丙胺（1毫克/千克）后的运动活性。使用了三组大鼠，每组的一半接受假处理，另一半接受每日1次、5次或10次的ECS。与对照组相比，接受重复ECS的大鼠对苯丙胺的运动反应显著增强，但对阿扑吗啡的反应未增强。这项研究表明，ECS的次数是ECS增强对苯丙胺运动反应的一个重要变量。
