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[原发性胆汁性肝硬化与特发性血小板减少性紫癜。一种新的关联]

[Primary biliary cirrhosis and idiopathic thrombopenic purpura. A new association].

作者信息

Chazot C, Vital Durand D, Sibille M, Levrat R

出版信息

Rev Med Interne. 1983 Jun;4(2):173-5. doi: 10.1016/s0248-8663(83)80011-3.

Abstract

A case of primary biliary cirrhosis with stage III histological changes associated with an asymptomatic thrombocytopenic purpura with raised antiplatelet antibody levels is described. This new association of two conditions in which an autoimmune participation is generally accepted suggests a predisposition to this form of disease and/or the intervention of common trigger factors; however, an analysis of known etiological mechanisms does not exclude the possibility of a fortuitous association.

摘要

本文描述了一例原发性胆汁性肝硬化患者,其组织学改变为Ⅲ期,伴有无症状性血小板减少性紫癜,抗血小板抗体水平升高。这两种疾病的新关联,其中自身免疫参与通常被认可,提示了对这种疾病形式的易感性和/或共同触发因素的干预;然而,对已知病因机制的分析并不排除偶然关联的可能性。

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