Janvier M, Clauvel J P, Tobelem G, Vainchenker W, Seligmann M, Boiron M
Nouv Rev Fr Hematol (1978). 1983;25(4):253-7.
The authors reported the effect of high dose intravenous immunoglobulin therapy in 18 patients with chronic autoimmune thrombocytopenic purpura. A good but transitory response was observed in 60% of the cases. The intensity of the response was variable, the duration was between 11 and 26 days. The mechanism of the effect of this therapy is poorly understood. Since this therapy is expensive and the response inconsistent and transitory, the indications are limited.
作者报告了大剂量静脉注射免疫球蛋白疗法对18例慢性自身免疫性血小板减少性紫癜患者的疗效。60%的病例观察到良好但短暂的反应。反应强度各异，持续时间在11至26天之间。这种疗法的作用机制尚不清楚。由于该疗法费用昂贵且反应不一致、短暂，其适应证有限。
