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[自然发育过程中以及酒精性动物后代的感觉运动皮层结构组织特征]

[Features of the structural organization of the sensomotor cortex during natural development and among the progeny of alcoholic animals].

作者信息

Popova E N

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(7):1053-6.

PMID:6684858
Abstract

Rats of both sexes were given alcohol for four months (15% alcohol in the first month, and 25% alcohol later on). The 21- and 30-day-old rats born to these parents displayed, in addition to the inhibited maturation of the sensomotor cortex, dystrophic alterations in neurons and their dendrites, which were more pronounced in the 21-day-old animals. Despite the signs of a reparative character, the cortical structural organization remained impaired as long as one month after birth. This indicates that alcohol intoxication interferes with postnatal development of the brain in their offspring.

摘要

对雌雄大鼠给予酒精四个月(第一个月给予15%的酒精,之后给予25%的酒精)。这些亲本所生的21日龄和30日龄大鼠,除感觉运动皮层成熟受到抑制外,神经元及其树突还出现了营养不良性改变,在21日龄动物中更为明显。尽管有修复特征的迹象,但出生后长达一个月,皮质结构组织仍受损。这表明酒精中毒会干扰其后代大脑的产后发育。

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