Hilton P, Stanton S L
Br J Obstet Gynaecol. 1983 Oct;90(10):919-33. doi: 10.1111/j.1471-0528.1983.tb06764.x.
Urethral pressure measurements were recorded at rest and during stress by a microtransducer technique in 20 women without urinary symptoms and 120 women with urodynamically proven genuine stress incontinence. In the symptom-free women the resting profile values were largely maintained during stress, as a consequence of 100% transmission of intra-abdominal pressure rises to the proximal three-quarters of the functional urethral length. Whilst the majority maintained continence at the bladder neck level, 25% of these controls showed evidence of bladder neck opening during stress. The stress-incontinent patients showed a deficiency of pressure transmission ratios which appeared to have an 'all or none' character in the determination of symptoms. The amplitude and stability of the maximum urethral closure pressure at rest, the extent of urethral closure pressure lost in response to stress, and the extent of intrabdominal pressure rises interact to determine the severity of symptoms or 'margin to continence'.
采用微型传感器技术，对20名无尿路症状的女性和120名经尿动力学证实为真性压力性尿失禁的女性，在静息状态和应激状态下进行尿道压力测量。在无症状女性中，由于腹内压升高100%传递至功能性尿道近端四分之三，静息状态下的压力曲线值在应激过程中基本保持不变。虽然这些对照组中的大多数在膀胱颈水平保持控尿，但其中25%的人在应激时有膀胱颈开放的迹象。压力性尿失禁患者的压力传递率不足，在症状的决定方面似乎具有“全或无”的特征。静息时最大尿道闭合压的幅度和稳定性、应激时尿道闭合压丧失的程度以及腹内压升高的程度相互作用，共同决定症状的严重程度或“控尿余量”。
