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实验性小鼠血吸虫病中的宿主抗原现象。III. 从小鼠转移至仓鼠的寄生虫的破坏

The host antigen phenomenon in experimental murine schistosomiasis. III. Destruction of parasites transferred from mice to hamsters.

作者信息

Boyer M H, Kalfayan L J, Ketchum D G

出版信息

Am J Trop Med Hyg. 1977 Mar;26(2):254-7. doi: 10.4269/ajtmh.1977.26.254.

DOI:10.4269/ajtmh.1977.26.254
PMID:66880
Abstract

The surgical transfer of 23- to 28-day-old Schistosoma mansoni from donor mice to the mesenteric vessels of outbred hamsters is followed by recovery of 70% of the transferred trematodes 30 days later. Prior immunization of hamsters with mouse erythrocytes results in anti-mouse erythrocyte antibody titers of greater than 1:4,096 and death of 98% of the parasites. Destruction is correlated with evidence of the presence of mouse antigenic determinants on the surfaces of schistosomes from donor mice.

摘要

将23至28日龄的曼氏血吸虫从供体小鼠手术转移至远交系仓鼠的肠系膜血管后,30天后可回收70%的转移吸虫。事先用小鼠红细胞免疫仓鼠会导致抗小鼠红细胞抗体效价大于1:4,096,且98%的寄生虫死亡。这种破坏与来自供体小鼠的血吸虫表面存在小鼠抗原决定簇的证据相关。

相似文献

1
The host antigen phenomenon in experimental murine schistosomiasis. III. Destruction of parasites transferred from mice to hamsters.实验性小鼠血吸虫病中的宿主抗原现象。III. 从小鼠转移至仓鼠的寄生虫的破坏
Am J Trop Med Hyg. 1977 Mar;26(2):254-7. doi: 10.4269/ajtmh.1977.26.254.
2
The host antigen phenomenon in experimental murine schistosomiasis. II. Failure to demonstrate destruction of parasites transferred from hamsters to mice.实验性小鼠血吸虫病中的宿主抗原现象。II. 未能证明从仓鼠转移至小鼠的寄生虫被破坏。
J Immunol. 1976 Apr;116(4):1093-5.
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Survival of schistosomula (Schistosoma mansoni) transferred from hamsters to mice immunized against the donor host.从仓鼠转移至针对供体宿主进行免疫的小鼠体内的曼氏血吸虫童虫的存活情况。
J Parasitol. 1976 Feb;62(1):159-61.
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Schistosoma mansoni: a comparison of mouse and rat worms with respect to host antigens detected by the technique of transfer into hamsters.曼氏血吸虫:关于通过移植到仓鼠体内的技术检测到的宿主抗原,对小鼠和大鼠体内的虫体进行比较。
Int J Parasitol. 1976 Aug;6(4):355-62. doi: 10.1016/0020-7519(76)90059-x.
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Nicarbazin in schistosome infections: I. Antibody formation in mice and hamsters infected with Schistosoma mansoni.尼卡巴嗪在血吸虫感染中的作用:I. 感染曼氏血吸虫的小鼠和仓鼠体内抗体的形成
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An indirect haemagglutination reaction for the demonstration of Schistosoma mansoni circulating anodic antigen.
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The host antigen phenomenon in experimental murine schistosomiasis: the transfer of 3-week old Schistosoma mansoni between two inbred strains of mice.实验性小鼠血吸虫病中的宿主抗原现象:在两种近交系小鼠之间转移3周龄曼氏血吸虫。
Int J Parasitol. 1976 Jun;6(3):235-8. doi: 10.1016/0020-7519(76)90040-0.
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Detection of Schistosoma mansoni M antigen in circulating immune-complexes and in kidneys of infected hamsters.在感染仓鼠的循环免疫复合物和肾脏中检测曼氏血吸虫M抗原。
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Schistosoma mansoni: host antigen occurrence on worms recovered from laboratory vertebrate animals.曼氏血吸虫:从实验室脊椎动物体内获取的虫体上宿主抗原的出现情况
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Schistosoma mansoni: acquired immunity in mice and hamsters using antigens of Fasciola hepatica.
Exp Parasitol. 1977 Aug;42(2):348-55. doi: 10.1016/0014-4894(77)90092-3.

引用本文的文献

1
Schistosomiasis: progress and problems.血吸虫病:进展与问题
World J Gastroenterol. 2000 Feb;6(1):12-19. doi: 10.3748/wjg.v6.i1.12.
2
A model system for the study of antigen secretion by adult Schistosoma mansoni in vivo.一种用于研究成年曼氏血吸虫体内抗原分泌的模型系统。
Parasitol Res. 1994;80(2):154-8. doi: 10.1007/BF00933784.