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一种青蛙前肾肿瘤细胞系的核型分析

Karyotype analysis of a frog pronephric tumor cell line.

作者信息

Przybelski R J, Tweedell K S

出版信息

Exp Cell Biol. 1978;46(5):289-97. doi: 10.1159/000162905.

Abstract

Pronephric tumor cell lines, established from explants of a herpes virus induced frog renal adenocarcinoma, were shown to have a aneuploid modal chromosome number of 39. A karyotypic analysis of one line demonstrated the presence of abnormal chromosomes and chromosomal aberrations not previously reported for Lucké tumor cells. The cell line was characterized by two marker chromosomes of high incidence, but there was no evidence of a stemline population of tumor cells.

摘要

从疱疹病毒诱导的青蛙肾腺癌外植体建立的前肾肿瘤细胞系,其非整倍体众数染色体数为39。对其中一个细胞系的核型分析表明存在异常染色体和染色体畸变,这些在以前的勒克肿瘤细胞中未被报道过。该细胞系的特征是有两条高发生率的标记染色体,但没有证据表明存在肿瘤细胞的主干群体。

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